ENGLEWOOD, Colo. — Running back Phillip Lindsay needs surgery after injuring his wrist and faces a three-to-four month rehab process, Head Coach Vance Joseph announced Wednesday.

Joseph said Lindsay will "most likely" be placed on injured reserve this week to allow the Broncos to bring a healthy player up to the 53-man roster.

"He's had a great year, obviously," Joseph said. "To go out that way is not good for him, but it doesn't take from the year he's had. He's had a great year. He's a great find for this football team, and moving forward he's going to be a great player for this franchise. He wants to finish it obviously and go to the Pro Bowl, but he can't because of the injury. We all know what he did this year."

Joseph did not say whether Lindsay suffered a fracture in his hand, as well.

Lindsay suffered the injury during the third quarter of the Broncos' "Monday Night Football" game in Oakland. He did not return to the game.

"It sucks," said quarterback Case Keenum on Wednesday in response to the news. "Hate that after the year he's had and just the spark he gives us, not just on the field — but in the locker room, the type of guy he is. Not the ending you want for a guy like that. It's tough, but he'll bounce back. I know he'll come back stronger. He's a guy that's probably fighting to play and probably getting held back. He's a great human. I really enjoy being around him and the spark he brings us. We'll miss him."

Joseph also said it doesn't appear Andre Holmes (ankle) will play Sunday against the Chargers.

"I'm not sure," Joseph said. "He's really sore. It's a high-ankle sprain, so we'll see how tomorrow looks. But right now it doesn't look good."

Cornerback Brendan Langley (concussion) and tight end Matt LaCosse (ankle) were both limited in Wednesday's practice.

Joseph said Langley has not yet passed concussion protocol.