If you need a running back—especially to replace Marshawn Lynch, who just had surgery for a hernia—then Seahawks RB Thomas Rawls has to be your top target. Staying in the division, Shaun Draughn for the 49ers was a big weapon for San Francisco in the passing game, with 11 targets and eight catches against Seattle, and he's had 28 carries in the pas two games. The 49ers play the daunting Cardinals defense this week, but he could once again be a target as a check-down receiver against an Arizona secondary that will make this difficult for QB Blaine Gabbert and his wide receivers.
And I think with the knowledge that Broncos QB Brock Osweiler will start the next two weeks, grab C.J. Anderson and play him. If Darren McFadden is still out there in your league, he is worth a play with Romo back, too. Finally, the Texans are playing better, and Alfred Blue was given 24 touches Sunday. He didn't do well yardage-wise, but he got into the end zone and facing a league-last Saints defense this week, he's worth a claim.
At wide receiver, Cody Latimer had his first touchdown of his career Sunday for the Broncos. It's time to play him more. Panthers WR Devin Funchess is getting the ball tossed his way by Cam Newton, and Ravens WR Kamar Aiken is still out there in many leagues, though losing Joe Flacco for the season doesn't bode well for him or the other receivers.
Quarterback Jameis Winston is really coming on late for the Buccaneers, and he faces a bad Eagles defense in Week 12. He may be a good option if you need it. Texans QB Brian Hoyer has recovered from a concussion and should be ready to go for Houston against New Orleans and their aforementioned defense. Also Josh McCown leads the Browns against the Ravens this week at home, and Baltimore seems to be in a tailspin as injuries pile up. He may have a good week again.
And finally, if you want a defense, grab the Chiefs. They are playing really well, and they have a favorable schedule to finish off the season.